Kidney Stones (Nephrolithiasis)

Kidney stones are hard masses that form from concentrated crystals found in the urine.  Normally the substances that make up kidney stones are dilute in the urine.  When the urine is concentrated, these substances clump together and form a nidus for kidney stone formation or nephrolithiasis.   The urine contains chemicals that inhibit and promote nephrolithiasis.  In some patients the balance between these chemicals is off and stones develop.

The majority of kidney stones contain calcium but there are several types of stones.  Stones are classified into two major groups, those that are radio-opaque (visible on a standard x-ray) and those that are radiolucent (not visible on a standard x-ray, only visible on computerized tomography [CT] Scan).  Radio-opaque stones include Calcium Oxalate (monohydrate and dihydrate), Calcium Phosphate and Struvite stones.  Radiolucent stones include Uric Acid, 2,8-Dihydroxyadenine, Triamterene and Xanthine stones.

Stones typically form and rest in the kidney for long periods of time.  Stones that are located in the kidney can grow but rarely cause any symptoms.  Most patients are unaware that they even have kidney stones.  Pain typically occurs when the stone attempts to pass.  This means that the stone leaves the kidney and tries to travel down a narrow tube that drains the kidney termed the “ureter”.  Ureteral stones can be excruciating.  Depending on the size of the stone, the stone may or may not pass spontaneously.  Often times surgical removal of the stone is required.  Stones can also form in the urinary bladder, especially in those patients who have difficulty emptying their bladder secondary to a large prostate.  Treatment of kidney, ureteral and bladder stones involves both medical and surgical management.  Here at Urological Surgical Associates we are proud to offer all the latest kidney, ureteral and bladder stone treatment options including laser lithotripsy technology.

Medical Management:  

Dissolution:  Uric Acid stones can be dissolved with oral medications.  Uric Acid stones form in the presence of acidic urine (urine pH <6.0).  By manipulating the urine pH to above 6.5 with medications most uric acid stones will dissolve away over time.  These stones typically do not require surgical intervention.

Prevention:  This is the extremely important in patients who have had two or more stones.  Several dietary modifications and oral medications are prescribed to reduce or eliminate the chance of recurrent stone disease.  Important blood and 24 hour urine analyses are used to further evaluate patients with recurrent stones.  Depending on the type of stone and results of the lab tests any combination of the following treatments are prescribed:

1.    Increase overall fluid intake.  Goal should be drink enough fluids to urinate more than 2 liters of urine per day. 

2.    Decrease protein intake.  Excess protein intake can contribute to both uric acid and calcium based stones.  Limit intake to 6-8 ounces of beef, pork, poultry or fish per day.

3.    Decrease salt intake.  Excess salt intake can cause extra calcium to enter into the urine and thus lead to stone formation.

4.    Increase “Citrate” intake.  Citrate is commonly found in lemons.  Adding lemon juice to your fluids or drinking fresh lemonade can help inhibit the formation of stones

5.    Consume adequate calcium.  Contrary to popular belief stone formers should NOT restrict their calcium intake.  It is encouraged that you eat 2 servings of calcium rich foods daily.

6.    Decrease Oxalate Intake.  If you form calcium oxalate stones it is essential you limit your oxalate intake.  Oxalate containing foods include spinach, rhubarb, beets, chocolate, peanuts and teas.  For a more comprehensive list of foods please refer to our low oxalate diet form. 

7.    Prescription medications.  For some patients dietary modifications are not enough and oral medications may be required on a daily basis

Surgical Management: